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Plantar grasp reflex in high-risk infants during the first year of life
1First Pediatric Clinic, Aristotle University of Thessaloniki, Greece.
Insights
The absence of the plantar grasp reflex after 3 months may indicate spastic cerebral palsy. Primitive reflexes and postural reactions can predict specific neurodevelopmental abnormalities in infants.
Area of Science:
- Neuroscience
- Developmental Pediatrics
- Neurology
Background:
- Primitive reflexes are typically transient, disappearing as the central nervous system matures.
- Persistent primitive reflexes beyond expected age ranges often signal central nervous system pathology.
- However, the absence of certain reflexes, like the plantar grasp reflex, can also indicate neurological issues.
Purpose of the Study:
- To investigate the diagnostic significance of the plantar grasp reflex in early infancy.
- To determine the correlation between the absence of the plantar grasp reflex and the development of cerebral palsy.
- To assess the predictive value of primitive reflexes and postural reactions for neurodevelopmental abnormalities.
Main Methods:
- Analysis of data from one prospective and one retrospective study.
- Evaluation of the presence or absence of the plantar grasp reflex in infants.
- Correlation of reflex findings with subsequent diagnoses of cerebral palsy and other neurodevelopmental outcomes.
Main Results:
- The absence of the plantar grasp reflex from 3 months of age onwards significantly correlates with the development of spastic cerebral palsy.
- Specific patterns of primitive reflexes and postural reactions accurately predict certain types of cerebral palsy.
- The combination of reflex and reaction assessments offers a predictive tool for neurodevelopmental abnormalities.
Conclusions:
- The plantar grasp reflex's absence in infants older than 3 months is a potential indicator of spastic cerebral palsy.
- Assessing primitive reflexes and postural reactions is crucial for early identification and prediction of neurodevelopmental disorders.
- These neurological assessments can aid in the early diagnosis and classification of cerebral palsy.
Abstract:
For most primitive reflexes, retention of the reflex beyond the period when it should no longer be elicited suggests a pathologic process within the central nervous system. However, for certain primitive reflexes, such as the plantar grasp reflex, a negative response within the first months of life is suggestive of a neurologic abnormality. From the results of one prospective and one retrospective study, it is clearly indicated that the absence of the plantar grasp reflex from 3 months of age and on correlates with the development of spastic cerebral palsy. The specific combination of presence or absence of specific primitive reflexes, postural reactions, or both may accurately predict a specific type of cerebral palsy or neurodevelopmental abnormality.