Related Experiment Video
Updated: Aug 17, 2026

A Patient-Derived Xenograft Model for Venous Malformation
Published on: June 15, 2020
Treatment options for giant congenital naevi
1Dermatology, Royal Victoria Infirmary, Newcastle,UK. C.M.Lawrence@ncl.ac.uk
Abstract:
Giant congenital naevi (GCN) are disfiguring, potentially malignant pigmented naevi present at birth. The naevus cells in GCN are found throughout the dermis and sometimes penetrate the subcutaneous septa. It is claimed that superficial, more heavily pigmented and biologically different naevus cells reside in the upper dermis. Partial removal of these superficial naevus cells by dermabrasion, laser therapy, curettage or shave excision is less traumatic than excision surgery and produces an acceptable cosmetic result. However, none of these techniques or excision of GCN to superficial fat completely removes the risk of malignant transformation.
Related Concept Videos
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Varicose Veins II: Diagnostic Studies and Interprofessional Care

