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Related Experiment Videos

Effect of aneurysmectomy on left ventricular shape and function: case studies.

Y F Petrank1, H Azhari, J Lessick

  • 1The Heart System Research Center, Julius Silver Institute of Biomedical Engineering, Technion-IIT, Haifa, Israel.

Medical Engineering & Physics
|February 15, 2000
PubMed
Summary

Resecting left ventricular (LV) aneurysms significantly reduces LV size and improves heart function. This 3D analysis demonstrates improved global and regional function in the normal heart zones after aneurysmectomy.

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Area of Science:

  • Cardiovascular Surgery
  • Medical Imaging
  • Cardiac Mechanics

Background:

  • Left ventricular (LV) aneurysms significantly alter cardiac mechanics and geometry.
  • Surgical intervention aims to improve cardiac function and reduce adverse outcomes.
  • Detailed three-dimensional (3D) analysis is crucial for understanding complex conformational changes.

Purpose of the Study:

  • To evaluate the 3D conformational changes in patients with large anterior LV aneurysms before and after aneurysmectomy.
  • To assess the impact of aneurysm resection on LV size, global function, and regional myocardial function.

Main Methods:

  • Utilized 3D Cine-computerized tomography (CT) to reconstruct the LV in 3D from endocardial and epicardial tracings.
  • Calculated LV thickness, percent thickening, and regional wall stress index using a 3D-volume element approach.

Related Experiment Videos

  • Compared pre-operative and two-year post-operative measurements in three patients.

    • Main Results:

    • Aneurysmectomy significantly reduced end-diastolic volume (257 to 183 ml) and end-systolic volume (172 to 92 ml).
    • Ejection fraction improved from 34% to 51% post-surgery.
    • Endocardial aneurysm area decreased, while the percent thickening of the normal LV zone significantly increased.

    Conclusions:

    • Resection of LV aneurysms effectively reduces aneurysmal area and LV size.
    • Surgical intervention improves both global and regional function of the remote normal LV zones.
    • The 3D analysis approach provides valuable insights for optimizing surgical techniques for LV aneurysm repair.