Clinical evaluation of a pit and fissure sealant for young adults

A BIS-GMA sealant, Nuva-Seal, failed to provide a statistically significant treatment for subjects 17 to 23 years of age. Sealant therapy cannot be considered a cost-effective factor for this age group. Retention of the more visible tinted version of the sealant was inferior to that of the clear commercial variety. This unexpected disparity in retention of the clear and tinted sealants underscores the importance of employing the exact product of interest to the dental profession when conducting the clinical trial.