Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Medulloblastoma.

A T Reddy1, R J Packer

  • 1Division of Pediatric Neurology, The Children's Hospital of Alabama, University of Alabama at Birmingham, USA. areddy@peds.uab.edu

Current Opinion in Neurology
|February 17, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MRI Features of Histologically Diagnosed Supratentorial Primitive Neuroectodermal Tumors and Pineoblastomas in Correlation with Molecular Diagnoses and Outcomes: A Report from the Children's Oncology Group ACNS0332 Trial.

AJNR. American journal of neuroradiology·2019
Same author

Treatment of pediatric cerebral radiation necrosis: a systematic review.

Journal of neuro-oncology·2016
Same author

Remarkable oxide ion conductivity observed at low temperatures in a complex superstructured oxide.

Advanced materials (Deerfield Beach, Fla.)·2010
Same author

CNS germ cell tumor (CNSGCT) of childhood: presentation and delayed diagnosis.

Neurology·2007
Same author

NF1 plexiform neurofibroma growth rate by volumetric MRI: relationship to age and body weight.

Neurology·2007
Same author

Treatment strategies for medulloblastoma and primitive neuroectodermal tumors.

Neurosurgical focus·2006
Same journal

Movement disorders and Parkinson's disease: collaborative and interdisciplinary research to advance understanding of neural circuit dysfunction, pathophysiology, and care: new horizons in technology, neuroimaging, neurophysiology, and genetics toward personalized medicine.

Current opinion in neurology·2026
Same journal

Editorial introduction.

Current opinion in neurology·2026
Same journal

Multimodal mapping of balance dysfunction in Parkinson's disease: a consensus roadmap for research and intervention.

Current opinion in neurology·2026
Same journal

Tourette syndrome: brain neurophysiology, circuit dysfunction, and neuromodulation across invasive and noninvasive approaches.

Current opinion in neurology·2026
Same journal

Dystonia: from phenotypes to genetics and therapeutic advances.

Current opinion in neurology·2026
Same journal

What can we learn from eye movements in movement disorders and Parkinson's disease?

Current opinion in neurology·2026
See all related articles

Multi-modal therapy, including radiation and chemotherapy, has improved outcomes for medulloblastoma patients. Ongoing research into medulloblastoma oncogenesis promises even better future treatments.

Area of Science:

  • Pediatric Oncology
  • Cancer Genomics
  • Radiation Oncology

Background:

  • Medulloblastoma treatment has advanced with multi-modal therapy.
  • Radiation and chemotherapy are established adjuvant treatments based on clinical trials.
  • A limited understanding of medulloblastoma's biology hinders further progress.

Purpose of the Study:

  • To summarize current treatment strategies for medulloblastoma.
  • To highlight the impact of multi-modal therapy on patient outcomes.
  • To underscore the importance of ongoing research into medulloblastoma oncogenesis.

Main Methods:

  • Review of recent large clinical trials in medulloblastoma treatment.
  • Analysis of current laboratory investigations into medulloblastoma biology.

Related Experiment Videos

  • Synthesis of data on survival rates and overall outcomes.
  • Main Results:

    • Multi-modal therapy has demonstrably improved survival rates and outcomes.
    • Radiation and chemotherapy are validated as effective adjuvant treatments.
    • Advances in understanding medulloblastoma oncogenesis are emerging.

    Conclusions:

    • Current multi-modal treatment approaches offer improved outcomes for medulloblastoma.
    • Further research into the biological basis of medulloblastoma is crucial for developing novel therapies.
    • Enhanced understanding of oncogenesis will likely lead to more effective treatments.