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Tracking cholinergic pathways from psychological and chemical stressors to variable neurodeterioration paradigms
1Department of Biological Chemistry, The Institute of Life Sciences, Hebrew University, Jerusalem, Israel. soreq@shum.huji.ac.il
Current Opinion in Neurology
|February 17, 2000
Abstract:
Cholinergic hyperexcitation can be induced by both acute psychological stress and exposure to acetylcholinesterase inhibitors. Both factors are known risk factors for delayed neurodeterioration processes such as Alzheimer's disease and Parkinson's disease. Recent publications on the involvement of cholinergic pathways in these and other neurodeterioration syndromes are reviewed.
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