Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The calculating brain: an fMRI study.

T C Rickard1, S G Romero, G Basso

  • 1Department of Psychology, University of California, San Diego, La Jolla 92093-0901, USA. trickard@ucsd.edu

Neuropsychologia
|March 11, 2000
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the brain basis of self-monitoring.

Cortex; a journal devoted to the study of the nervous system and behavior·2026
Same author

Surgical repair of bilateral lateral patellar luxation in a foal using block-recession trochleoplasty and polypropylene mesh reinforcement: Case report and review of literature.

Journal of equine veterinary science·2025
Same author

Allele-specific CRISPR-Cas9 editing of dominant epidermolysis bullosa simplex in human epidermal stem cells.

Molecular therapy : the journal of the American Society of Gene Therapy·2023
Same author

Corrigendum to "Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center": [ESMO Open 7 (2022) 100607].

ESMO open·2023
Same author

Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center.

ESMO open·2022
Same author

Metronidazole and alcohol.

British dental journal·2020
Same journal

Prevalence and modulation of rat off-track head scanning on linear tracks: possible implications for representational and dynamic properties of hippocampal place cells.

Neuropsychologia·2026
Same journal

Identifying networks within an fMRI multivariate searchlight analysis.

Neuropsychologia·2026
Same journal

Modulating sentence comprehension in people with aphasia through anodal tDCS: A double-blind randomized cross-over study.

Neuropsychologia·2026
Same journal

Deficient processing of regularity violations during visuospatial neglect: a visual mismatch negativity study.

Neuropsychologia·2026
Same journal

Seeing is believing: mental imagery amplifies moral, emotional, and motivational responding to mentally constructed hypothetical events.

Neuropsychologia·2026
Same journal

From Past Recall to Future Projection: What Does Verb Tense Production Reveal About Mental Time Travel in Alzheimer's disease?

Neuropsychologia·2026
See all related articles

Functional magnetic resonance imaging (fMRI) reveals specific brain regions involved in basic numerical computation. Key areas like Brodmann's area 44 show activation during arithmetic tasks, challenging previous findings.

Area of Science:

  • Neuroscience
  • Cognitive Psychology
  • Neuroimaging

Background:

  • Basic numerical computation is fundamental to cognition.
  • Previous studies have implicated various brain regions, including the angular and supramarginal gyri, in arithmetic processing.

Purpose of the Study:

  • To investigate the neural correlates of basic numerical computation using functional magnetic resonance imaging (fMRI).
  • To identify specific brain areas activated during simple arithmetic and numerical magnitude judgment tasks.

Main Methods:

  • fMRI scanning was conducted on college students performing three tasks: simple arithmetic, numerical magnitude judgment, and a perceptual-motor control task.
  • Brain activation patterns were analyzed for each task relative to control conditions.

Related Experiment Videos

Main Results:

  • Simple arithmetic tasks consistently activated bilateral Brodmann's area 44, dorsolateral prefrontal cortex (areas 9 and 10), inferior and superior parietal areas, and lingual and fusiform gyri.
  • Activation was more pronounced in the left hemisphere at Brodmann's area 44 and parietal cortices.
  • Contrary to some hypotheses, the angular and supramarginal gyri showed deactivation during arithmetic verification tasks.

Conclusions:

  • The findings confirm some existing hypotheses about the neural basis of numerical cognition while prompting revisions of others.
  • Specific brain regions, notably Brodmann's area 44 and parietal areas, are crucial for basic numerical computation.
  • Future research should explore these identified areas and re-evaluate the role of previously implicated regions like the angular and supramarginal gyri.