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Signal transduction: Life, the universe and ... development
1MRC Laboratory for Molecular Cell Biology, University College London, London, WC1E 6BT, UK.
Current Biology : CB
|February 19, 2000
Abstract:
Glycogen synthase kinase 3 (GSK-3) is a key component of the Wnt signalling pathway, among others, and is known to be regulated by inhibition. Now a novel, dual specificity protein kinase known as Zaphod kinase has been discovered that activates GSK-3 by tyrosine phosphorylation.