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[Immune responses in C57BL/6J mice with the inverted pattern of behavior during social conflict]

L V Devoĭno1, E L Al'perina, T A Pavina

  • 1Institute of Physiology, Siberian Branch of the Russian Acad. Med. Sci., Novosibirsk, Russia.

Inversion of aggressive behaviour into a submissive one led to immunosuppression in C57BL/6J mice as well as in those mice which did not change their behaviour, whereas inversion of submissive behaviour into aggressive one resulted in immunostimulation. A possibility to influence immune response changing the brain neurochemical pattern by reversing behaviour under conditions of a social conflict, is discussed.

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