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Effect of crude extracts of Erythrina americana Mill. on aggressive behavior in rats
M E Garín-Aguilar1, J E Luna, M Soto-Hernández
1ENEP-Iztacala, UNAM. Tlalnepantla, Edo. de Méx., Mexico.
Journal of Ethnopharmacology
|February 25, 2000
Abstract:
Three alkaloid fractions were obtained from seeds of Erythrina americana: free alkaloids in hexane, free alkaloids in methanol and liberated alkaloids. The pharmacological evaluation of these fractions on rats showed that, administered in a dose of 3 mg/kg, the three fractions diminished the aggressive behavior. This is comparable when diazepam is used as a control. An interaction between the cholinergic and GABAergic system could be suggested.
