Related Experiment Videos
Toxicology and evaluation of microcystins
1Centre for Coastal Pollution and Conservation, Department of Biology and Chemistry, City University of Hong Kong, Kowloon.
Therapeutic Drug Monitoring
|February 25, 2000
Abstract:
This paper reviews the toxicity and tumor-promoting properties of microcystins. Methods for screening and/or identification of microcystins in environmental samples are discussed and compared. Specific emphasis is placed on newly developed extraction/detection methods, e.g., solid phase microextraction (SPME) technique, and capillary electrophoresis coupled with laser-induced fluorescence detection. The results of a kinetic analysis of the effects of microcystins on phosphorylase-a binding to phosphatase-2A using a surface plasmon resonance biosensor are also presented.