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Visual Evoked Potential Recording in a Rat Model of Experimental Optic Nerve Demyelination
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The potential for vigabatrin-induced intramyelinic edema in humans

J A Cohen1, R S Fisher, M G Brigell

  • 1Mellen Center for Multiple Sclerosis Treatment and Research, Department of Neurology, Cleveland Clinic Foundation, Ohio 44195, USA.

Epilepsia
|February 26, 2000
PubMed
Summary

Vigabatrin (VGB) is an antiepilepsy drug effective for seizures. Despite animal studies showing potential for intramyelinic edema (IME), extensive human data reveals no confirmed cases of VGB-induced IME.

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