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Neural network application in the discrimination of benign from malignant gastric cells
P Karakitsos1, A Pouliakis, K Koutroumbas
1Department of Cytology, St. Olga Hospital, Greece.
Objective:
To investigate the potential value of morphometry and neural networks for the discrimination of benign from malignant gastric lesions.
Study Design:
One thousand cells from 19 cases of cancer, 19 cases of gastritis and 56 cases of ulcer were selected as a training set, and an additional 4,000 cells from the same cases of cancer, gastritis and ulcer were used as a test set. Images of routinely processed gastric smears stained by the Papanicolaou technique were analyzed by a custom-made image analysis system.
Results:
Application of the neural network gave correct classification in 96% of benign cells and 89% of malignant cells.
Conclusion:
The results indicate that the use of neural networks and image morphometry may offer useful information concerning the potential of malignancy in gastric cells.