Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cataract development after trabeculectomy with mitomycin C: a 1-year study.

L Daugeliene1, T Yamamoto, Y Kitazawa

  • 1Department of Ophthalmology, Gifu University School of Medicine, Gifu-ken, Japan.

Japanese Journal of Ophthalmology
|March 4, 2000
PubMed
Summary

Trabeculectomy with mitomycin C can cause slight cataract changes in the crystalline lens as early as one month post-surgery. These changes in lens transparency gradually worsen over the following eleven months.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient ischemic injury in the rat retina caused by thrombotic occlusion-thrombolytic reperfusion.

Investigative ophthalmology & visual science·2000
Same author

Risk factors for visual field damage progression in normal-tension glaucoma eyes.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·1999
Same author

Effect of trabeculectomy on visual field in progressive normal-tension glaucoma.

Japanese journal of ophthalmology·1998
Same author

An image analysis study of cataract development after trabeculectomy with mitomycin C.

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde·1998
Same author

[Semidiscoid lateral meniscus].

Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica·1992
Same author

Midline malignant B-cell lymphoma with leukemic transformation.

Cancer·1992

Area of Science:

  • Ophthalmology
  • Glaucoma Surgery
  • Cataract Research

Background:

  • Trabeculectomy with mitomycin C is a common glaucoma surgery.
  • Cataract development is a potential complication after ocular surgery.

Purpose of the Study:

  • To quantitatively measure cataract changes in the crystalline lens after trabeculectomy with mitomycin C.
  • To identify clinical factors associated with post-trabeculectomy cataract development.

Main Methods:

  • Prospective study of 41 phakic patients undergoing trabeculectomy with mitomycin C.
  • Lens transparency was assessed using an anterior segment analysis system preoperatively and at 1, 3, and 12 months postoperatively.
  • Multivariate regression analysis was used to correlate cataract development with clinical factors.

Related Experiment Videos

Main Results:

  • Cataract changes were observed as early as one month postoperatively, initially in the anterior lens segment.
  • Deeper lenticular areas showed increased light scattering intensity over time.
  • Several clinical factors were found to be associated with cataract development.

Conclusions:

  • Trabeculectomy with mitomycin C is associated with the development of slight cataracts.
  • These cataractous changes progress in extent and intensity during the first year after surgery.
  • Understanding these changes is crucial for managing patients post-glaucoma surgery.