[Effect of insulin on the development of the tooth germ in mice]

After recalling the interactions affecting dental differentiation, the authors analyze the effects of various concentrations in insulin on dental rudiments cultivated in vitro. They found: an oedema causing histological lesions, no anticipation of cell differentiation or stimulation of collagen secretion, a decrease in mitotic activity but stimulation of thymidine 3H incorporation after short contact times.