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Compliance and noncompliance in kidney transplant patients: cues for transplant coordinators
1Kontracted Health-Associated Services LLP, Brooklyn, NY, USA.
Abstract:
Maximizing kidney transplant patients' long-term compliance with immunosuppressants is a major challenge to transplant coordinators. Although previous research has found substantial proportions of recipients to be noncompliant, predictors of noncompliance and characteristics of noncompliers remain unclear. In this study of more than 1400 kidney transplant patients, we found noncompliance to be associated with patient and transplant characteristics and with patient beliefs concerning the efficacy of immunosuppressants. Three distinct profiles of noncompliers were identified: accidental noncompliers, invulnerables, and decisive noncompliers. This information can be used by transplant coordinators to recognize cues that predict noncompliance and to work with at-risk patients to forestall or remedy noncompliant behavior.
Insights
Kidney transplant recipients
Area of Science:
- Nephrology
- Transplantation
- Behavioral Science
Background:
- Long-term adherence to immunosuppressants is crucial for kidney transplant success.
- Predictors and characteristics of noncompliance in kidney transplant recipients are not well understood.
Purpose of the Study:
- To identify predictors of immunosuppressant noncompliance in kidney transplant patients.
- To characterize different profiles of noncompliant patients.
Main Methods:
- Analysis of data from over 1400 kidney transplant patients.
- Investigated associations between noncompliance, patient/transplant factors, and patient beliefs.
Main Results:
- Noncompliance is linked to specific patient and transplant characteristics.
- Patient beliefs about immunosuppressant efficacy are associated with noncompliance.
- Three noncomplier profiles identified: accidental, invulnerable, and decisive.
Conclusions:
- Understanding noncompliance predictors and patient profiles aids transplant coordinators.
- Targeted interventions can be developed to improve adherence in at-risk kidney transplant recipients.
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