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Effect of honey on multidrug resistant organisms and its synergistic action with three common antibiotics
S Karayil1, S D Deshpande, G V Koppikar
1Department of Microbiology, T.N.M.C. & B.Y.L. Nair Charitable Hospital, Mumbai.
Journal of Postgraduate Medicine
|March 7, 2000
Abstract:
A total of 15 bacterial strains (7 Pseudomonas & 8 Klebsiella species) isolated from various samples which showed multi-drug resistance were studied to verify in vitro antibacterial action of honey on the principle of Minimum Inhibitory Concentration (MIC) & its synergism with 3 common antibiotics--Gentamicin, Amikacin & Ceftazidime. The MIC of honey with saline for both organisms was found to be 1:2. The synergistic action was seen in the case of Pseudomonas spp. and not with Klebsiella spp.