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Cytomegalovirus infection may cause ureteral necrosis
N Peretti1, M H Saïd, R Bouvier
1Département de Pédiatrie, Hôpital Edouard Herriot and Université Claude Bernard, Lyon, France.
Transplantation
|March 9, 2000
Abstract:
Cytomegalovirus (CMV) infection has protean presentation among immunocompromised patients, but the urinary tract is rarely involved. We report a case of extensive ureteral necrosis in a renal transplant, 12-year-old patient with typical histological feature of CMV inclusions. The role of CMV was confirmed by immunohistochemical analysis and concomitant CMV DNA detection in peripheral blood leukocytes by polymerase chain reaction analysis. CMV infection can, therefore, be regarded as a possible cause of ureteral necrosis in renal transplant recipients.