Related Experiment Videos
Tyrosine sulfation: a modulator of extracellular protein-protein interactions
1Departments of Molecular and Cell Biology, University of California, Berkeley, CA 94720, USA.
Chemistry & Biology
|March 14, 2000
Abstract:
Tyrosine sulfation is a post-translational modification of many secreted and membrane-bound proteins. Its biological roles have been unclear. Recent work has implicated tyrosine sulfate as a determinant of protein-protein interactions involved in leukocyte adhesion, hemostasis and chemokine signaling.