A simple method for the in vitro study of the virucidal activity of disinfectants

For the study of the virucidal activity of a disinfectant by the gel filtration or the dilution methods, the concentration of virus has to be high enough to determine a decrease in titer of at least 4 logarithm units. A filtration technique for rapid separation of the disinfectant and the virus is described that overcome this limitation. The method is applicable to any chemical compound and gives results equivalent to those of the techniques required by the French norms (NF T 72-180).