Related Experiment Videos
[Eruptive xanthogranulomatosis in a trisomy 21 patient with acute lymphoblastic leukemia]
S Sarthou-Bruere1, B Milpied-Homsi, B Mahe
1Clinique Dermatologique, CHU, Place Alexis-Ricordeau, 44093 Nantes Cedex 1.
Background:
Juvenile xanthogranulomas may be associated with myeloproliferative disorders, usually juvenile chronic granulocytic leukemia.
Case Report:
We report the case of a 25-year-old man with Down's syndrome who presented eruptive xanthogranulomas. At this time, the patient was being treated for acute lymphocytic leukemia. The eruption increased with an extensive unusual "satellite" arrangement despite apparent remission of the acute leukemia. Leukemia relapse occurred some months later.
Discussion:
This case had an unusual clinical presentation. It also suggests their might be a link between the clinical course of lymphocytic leukemia and juvenile xanthogranuloma.