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Updated: Aug 11, 2026
08:03
Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice
Published on: April 15, 2014
Summary
Measles is a serious concern in Port Moresby, particularly for young children, causing severe complications like pneumonia. Measles vaccination could significantly reduce disease impact and healthcare costs.
Area of Science:
- Epidemiology
- Public Health
- Pediatrics
Background:
- Measles poses a significant health burden in Port Moresby, Papua New Guinea.
- The disease predominantly affects children under three years of age.
Purpose of the Study:
- To evaluate the severity and impact of measles in Port Moresby.
- To analyze measles case data from hospital outpatients, urban clinics, and hospital admissions.
- To estimate the economic cost of measles and the potential benefits of vaccination.
Main Methods:
- Analysis of 101 outpatient cases, 26 urban clinic cases (1974), and 277 inpatient cases (1973-74).
- Assessment of complication rates, mortality, and treatment costs.
- Estimation of potential cost savings from measles vaccination.
Main Results:
- The majority of measles cases occurred in children under three years old.
- Common complications included pneumonia (61% of outpatients, 73% of inpatients), gastro-enteritis (28% of outpatients, 26% of inpatients), and dehydration (22% of inpatients).
- A case mortality rate of 2.2% was observed among admitted patients, with pneumonia being a common factor in deaths. Tuberculosis was noted in 4 children.
Conclusions:
- Measles presents a more severe challenge in Papua New Guinea compared to developed nations, though less severe than in many other developing countries.
- The estimated annual cost of measles treatment is K25,205.
- Introduction of measles vaccination could save K14,000 annually and prevent significant childhood illness and mortality.
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