Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

How do proteins fold?

Smith1

  • 1Department of Biological Science, Manchester Metropolitan University, Chester Street, Manchester, UK

Biochemical Education
|March 21, 2000
PubMed
Summary
This summary is machine-generated.

Understanding polypeptide folding is crucial for students to grasp how proteins achieve complex structures. This article reviews modern in vitro and cellular protein folding mechanisms within their biological context.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

FORUM: Enforcement Lessons from the Vienna Übahn.

Environmental management·1999
Same author

A High-Resolution Analysis of the nu3 and nu9 Absorption Bands of Difluoromethane.

Journal of molecular spectroscopy·1999
Same author

A Quantitative Method for Estimating Probable Public Costs of Hurricanes.

Environmental management·1999
Same author

Dynamic holographic imaging of the beating human heart

Circulation·1999
Same author

Dynamic holographic imaging of the beating human heart : february 9, 1999

Circulation·1999
Same author

Code Growth, Explicitly Defined Introns, and Alternative Selection Schemes.

Evolutionary computation·1999
Same journal

Advances in experimental medicine and biology. Volumes 138-142 Published by Plenum Press, New York. Vol 138, $49.50; Vol 139, $59.50; Vol 140, $35; Vol 142, $49.50.

Biochemical education·2020
Same journal

The educational implications of biotechnology: A report on the seminar held at the National University of Singapore on June 5, 1981 by the IUBS Commission for Biological Education.

Biochemical education·2020
Same journal

A practical approach to the choice of a suitable detergent and optimal conditions for solubilizing a membrane protein.

Biochemical education·2000
Same journal

Oxidation of cholinesterase-inhibiting pesticides: A simple experiment to illustrate the role of bioactivation in the toxicity of chemicals.

Biochemical education·2000
Same journal

Carboxyfluorescein fluorescence experiments.

Biochemical education·2000
Same journal

A simple protocol to evaluate nitrogen utilisation in Saccharomyces cerevisiae.

Biochemical education·2000
See all related articles

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Structural Biology

Background:

  • Protein structure is essential for biological function.
  • Polypeptides must fold into specific higher-ordered structures to become functional proteins.
  • Understanding protein folding is a key challenge in molecular and structural biology.

Purpose of the Study:

  • To emphasize the importance of teaching polypeptide folding to students.
  • To summarize modern scientific understanding of protein folding processes.
  • To contextualize protein folding within broader biological principles.

Main Methods:

  • Review of current scientific literature on protein folding.
  • Synthesis of information regarding in vitro folding.
  • Analysis of in vivo (cellular) protein folding mechanisms.

Related Experiment Videos

Main Results:

  • Polypeptide chains fold into complex, functional protein molecules.
  • Both in vitro and in-cell folding pathways are influenced by various factors.
  • The process involves intricate biophysical and cellular mechanisms.

Conclusions:

  • Effective teaching of protein folding is vital for biological education.
  • Current models provide a comprehensive view of protein folding in different environments.
  • Further understanding of folding contributes to advancements in biotechnology and medicine.