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Updated: Oct 17, 2026

Tachycardia-Induced Cardiomyopathy As a Chronic Heart Failure Model in Swine
Published on: February 17, 2018
[Variants of hemodynamic response in transesophageal pacing in patients with chronic circulatory insufficiency]
Abstract:
Compared were hemodynamic responses to transesophageal pacing (TEP) in 86 patients with symptoms of chronic circulatory insufficiency (CCI) and 46 healthy individuals. Cardiac output was assessed by tetrapolar chest rheogram under stimulation and its discontinuation, and end diastolic pressure (EDP) in the left ventricle. Stroke volume was diminished in all the examinees. Cardiac output changed in different directions. Poststimulation recovery of cardiac output was different. Contribution of ejection period is discussed the prolongation of which indirectly indicates shorter time of diastole and, respectively, diastolic filling of cardiac chambers. EDP rose both in healthy controls and patients, being higher in the patients. The role of systolic and diastolic compensatory mechanisms in CCI development is considered.
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