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Diffusion-weighted MR imaging of the spinal cord
R Bammer1, F Fazekas, M Augustin
1Department of Neurology, Karl-Franzens University, Graz, Austria.
AJNR. American Journal of Neuroradiology
|March 24, 2000
Summary
Diffusion-weighted magnetic resonance imaging (DW-MRI) shows promise for spinal cord conditions. A new technique overcomes technical challenges, enabling high-resolution imaging for better diagnosis of intramedullary lesions.
Area of Science:
- Medical Imaging
- Neurology
- Radiology
Background:
- Diffusion-weighted magnetic resonance imaging (DW-MRI) can enhance diagnostic accuracy for spinal cord pathologies.
- Technical challenges have limited the clinical application of DW-MRI for the spinal cord.
Purpose of the Study:
- To evaluate a novel phase-navigated spin-echo diffusion-weighted interleaved echo-planar imaging sequence for spinal cord MRI.
- To assess the feasibility and diagnostic potential of high-resolution DW-MRI of the spinal cord.
Main Methods:
- A new DW-MRI sequence was tested in seven healthy volunteers and six patients with intramedullary lesions.
- High spatial resolution imaging of the spinal cord was performed.
Main Results:
- The novel sequence was successfully implemented for spinal cord DW-MRI.
- Distinct patterns of diffusion abnormalities were observed in patients with intramedullary lesions.
Conclusions:
- The developed DW-MRI technique is a viable method for high-resolution spinal cord imaging.
- Observed diffusion abnormalities suggest DW-MRI has significant diagnostic potential for spinal cord diseases.