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Updated: Jul 28, 2026

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A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Compartment syndrome complicating metastatic malignant melanoma
D J Simmons1, S M Wharton, R Waters
1Department of Plastic and Burns Surgery, Selly Oak Hospital, Birmingham University Hospitals NHS Trust, Birmingham, UK.
British Journal of Plastic Surgery
|March 30, 2000
Summary
Malignant melanoma metastasis rarely causes compartment syndrome. A case of arm compartment syndrome due to a slow-growing melanoma deposit was successfully treated with surgical excision, leading to full recovery.
Area of Science:
- Oncology
- Surgical Pathology
- Orthopedics
Background:
- Compartment syndrome is a surgical emergency often caused by trauma.
- Neoplastic involvement is an uncommon etiology for compartment syndrome.
Observation:
- A patient with metastatic malignant melanoma developed compartment syndrome in the arm.
- The cause was identified as a slow-growing, non-invasive metastatic melanoma deposit.
Findings:
- Surgical excision of the metastatic deposit was performed.
- The patient experienced an uneventful recovery following the procedure.
Implications:
- This case highlights the importance of considering rare causes of compartment syndrome in patients with a history of malignancy.
- Early diagnosis and surgical intervention are crucial for favorable outcomes in neoplastic compartment syndrome.
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