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Modeling of mosaic patterns in chimeric liver and adrenal cortex: algorithmic organogenesis?

G Landini1, P M Iannaccone

  • 1Oral Pathology Unit, School of Dentistry, The University of Birmingham, Birmingham, B4 6NN, England, UK. G.Landini@bham.ac.uk

FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
|April 1, 2000
PubMed
Summary

Organogenesis likely uses algorithmic instructions, not just deterministic ones. Computer simulations support a contact inhibition model for generating organ mosaic patterns, suggesting cell locomotion isn't required.

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