[Type 2 diabetes and large vessel disease]

Meal and post-meal period define the post-prandial state, which overall covers a little bit more than half daytime period. The post-prandial state is characterized by transient plasma variations in carbohydrates, lipids and hormones in direct relation with nutrient intake. These variations have an impact on the metabolism of several tissues. The post-prandial state in type 2 diabetic patients is considered as a crucial period, mainly due to the tissular toxicity of glucose. The established links between hyperglycemia and the rise of triglycerides-enriched particles can favor atherogenesis.