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Related Experiment Videos

Sudomotor abnormalities in reflex sympathetic dystrophy.

R C Chan1, T Y Chuang, F Y Chiu

  • 1Department of Physical Medicine and Rehabilitation, Taipei Veterans General Hospital, Taiwan, ROC.

Zhonghua Yi Xue Za Zhi = Chinese Medical Journal; Free China Ed
|April 4, 2000
PubMed
Summary
This summary is machine-generated.

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Abnormal sympathetic skin responses (SSRs) may indicate autonomic dysfunction in reflex sympathetic dystrophy (RSD) patients. SSR measurements offer insights into pathophysiologic changes and clinical evaluation of RSD.

Area of Science:

  • Neurology
  • Autonomic Nervous System Function
  • Pain Management

Background:

  • Reflex sympathetic dystrophy (RSD) can cause intractable pain and sweating abnormalities.
  • Autonomic dysfunction is a suspected component of RSD pathophysiology.
  • Sympathetic skin response (SSR) is a measure of sympathetic sudomotor function.

Purpose of the Study:

  • To investigate autonomic function in RSD patients using SSR.
  • To correlate SSR findings with different stages of RSD.
  • To evaluate the utility of SSR in the clinical assessment of RSD.

Main Methods:

  • SSR was recorded from the palms of 26 RSD patients and 22 controls.
  • RSD patients were staged (I, II, III) using three-phase bone scanning.

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  • Median nerve stimulation was used to elicit SSRs, with latency and amplitude ratios analyzed.

    • Main Results:

    • Stage I RSD showed significantly lower A/N hand amplitude ratios and higher A/N latency ratios.
    • Stage II RSD exhibited significantly higher A/N amplitude ratios.
    • Stage III RSD showed no significant changes in A/N amplitude or latency ratios; SSRs were unobtainable in some patients.

    Conclusions:

    • Abnormal SSRs are associated with autonomic disturbances in RSD.
    • SSR measurements can provide valuable pathophysiologic and clinical information for RSD.
    • SSR findings vary across different stages of RSD.