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Updated: Oct 17, 2026

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Published on: May 11, 2014
The "foamy" esophagus: a radiographic sign of Candida esophagitis
J W Sam1, M S Levine, S E Rubesin
1Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia 19104, USA.
Objective:
The purpose of this study was to describe the radiographic features of the "foamy" esophagus, a new sign of Candida esophagitis seen on double-contrast esophagography, in six patients.
Conclusion:
The foamy esophagus was characterized by innumerable tiny (1-3 mm), round lucencies (bubbles) that intermingled with the barium suspension along the top of the barium column, producing a layer of foam. Candida esophagitis should be strongly suspected when a foamy esophagus is detected on double-contrast esophagography, particularly in patients with underlying esophageal involvement by scleroderma.
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