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Updated: Aug 13, 2026
Heterotypic Three-dimensional In Vitro Modeling of Stromal-Epithelial Interactions During Ovarian Cancer Initiation and Progression
Published on: August 28, 2012
[Malignant gynecologic neoplasms in the Czech Republic 1986-1995]
Objective:
The incidence and mortality of malignant tumours of the uterine cervix, uterine body and ovary are analysed.
Design:
Retrospective study.
Setting:
Department of Obstetrics and Gynecology, Medical Faculty and Faculty Hospital, Charles University, Plzen.
Methods:
Analysis of relevant dates from the National Oncological Registry 1986-1995.
Results:
The incidence of the cervical carcinoma oscilated around 22 (22.7-21.6), the mortality slightly decreased (9.6-8.4). The incidence of the corpus carcinoma rose again (25.9-28.9), its mortality declined (7.4-6.9). The incidence of malignant ovarian tumours significantly increased (16.3-23.4), the mortality became slightly higher (14.8-16.2). The incidence of the ovarian carcinoma got ahead the incidence of the cervical carcinoma (23.4:21.6) and it occupied the second place after the corpus carcinoma.
Conclusions:
It is necessary to screen systematically gynecological malignant tumours and concentrate its treatment to specialized centers. Correct reports of these tumours and their precise staging is needed, too.
