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The ins and outs of EBV infection
G C Faulkner1, A S Krajewski, D H Crawford
1Depts of Medical Microbiology and Pathology, University of Edinburgh Medical School, Teviot Place, Edinburgh, UK EH8 9AG.
Trends in Microbiology
|February 7, 2001
Abstract:
Epstein-Barr virus (EBV) infects almost the entire adult population of the world. The success of this virus appears to be based on its ability to infect the B cell, rather than any other cell type. We review EBV B-cell tropism, and discuss the mechanisms by which the virus may gain access to, and egress from, B cells in the normal host.