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Behavioral Assessment of Manual Dexterity in Non-Human Primates
Published on: November 11, 2011
Behavioral test systems in marmoset monkeys
I H Philippens1, B P Melchers, T A Roeling
1Department of Pharmacology, TNO Pharma, Rijswijk, The Netherlands. philippens@pml.tno.nl
Abstract:
A number of neurobehavioral methods have been developed to test behavior in marmoset monkeys. These test systems are (1) the bungalow test, which quantifies spontaneous explorative behavior, (2) the hand-eye coordination test, which tests a learned task of coordinated motor behavior, and (3) the fear-potentiated startle response, which tests and quantifies pathological anxiety manifested by a response of fright. The test systems are extensively discussed, and the value of these test systems is exemplified by applying them to neurological disorders to register disease activity and drug efficacy.

