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Updated: Oct 17, 2026

Capillary Electrophoresis Separation of Monoclonal Antibody Isoforms Using a Neutral Capillary
Published on: January 16, 2017
Chiral separation by capillary electrochromatography
1Institute of Pharmaceutical Chemistry, Karl-Franzens University of Graz, Austria. guebitz@kfunigraz.ac.at
Abstract:
The state of art in chiral capillary electrochromatography is reviewed. Chiral separations by capillary electrochromatography were carried out using capillaries packed with chiral stationary phases or achiral stationary phases in combination with a chiral selector added to the mobile phase. Furthermore, the use of open tubular capillaries containing the chiral selector coated to the capillary wall was also reported. Among other separation principles moleculary imprinted polymers represent a challenging approach for chiral capillary electrochromatography. A recent trend is the use of polymeric continuous beds with a chiral selector incorporated.
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