[Wegener's granulomatosis]

The authors present a case of Wegener's granulomatosis in a 22 year-old female patient. They observed multi-organic changes concerning upper and lower respiratory tracts, skin, oral cavity, joints, kidneys. The diagnosis was confirmed in the Department for Infectious Diseases after two years of the beginning of the disease. The diagnosis was based on a course of the disease, histopathological changes of the skin, an increase of cANCA levels. CTX, prednisolon, cyclosporin and immunoglobulins i.v. for 5 days were used in the therapy. Apart from this symptomatic treatment was also introduced. The 14-month remission of the disease was obtained.