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Total synthesis of (+)-amphidinolide P. [corrected]
D R Williams1, B J Myers, L Mi
1Department of Chemistry, Indiana University, Bloomington 47405-7102, USA. williamd@indiana.edu
Organic Letters
|April 18, 2000
Abstract:
The convergent enantiocontrolled total synthesis of the 15-membered macrolactone (-)-amphidinolide P is reported. Key transformations include a Sakurai allylation, a Stille coupling for the formation of a fully functionalized acyclic precursor, and intramolecular transesterification.