Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peptide Bonds02:43

Peptide Bonds

78.6K
A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
78.6K
Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

7.1K
Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
7.1K
Protein Digestion01:02

Protein Digestion

106.9K
Protein digestion begins in the stomach, where the highly acidic environment can easily disrupt protein structure by exposing the peptide bonds of polypeptide chains. After polypeptide chains are broken into individual amino acids by a series of digestive enzymes, the amino acids are transported to the liver via the bloodstream to produce energy.
106.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Corticosterone dynamically regulates retrotransposable element expression in the rat hippocampus and C6 cells.

Neurobiology of stress·2021
Same author

Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis.

JAMA neurology·2020
Same author

Molecular endocrinology of female reproductive behavior.

Molecular and cellular endocrinology·2017
Same author

Autoradiographic Determination of Neurotransmitter Receptor Distributions in the Cerebral and Cerebellar Cortices <sup>1</sup> , <sup>2</sup>.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society·2017
Same author

Neuroepigenetics of stress.

Neuroscience·2014
Same author

Hippocampal gene expression changes underlying stress sensitization and recovery.

Molecular psychiatry·2013
Same journal

The merger of Regulatory Peptides and Peptides.

Regulatory peptides·2014
Same journal

WITHDRAWN: Effects of centrally-injected glucagon-like peptide-2 on gastric mucosal blood flow in rats; possible mechanisms.

Regulatory peptides·2014
Same journal

Hypothalamic-pituitary thyroid axis alterations in female mice with deletion of the neuromedin B receptor gene.

Regulatory peptides·2014
Same journal

Resistin induces lipolysis and suppresses adiponectin secretion in cultured human visceral adipose tissue.

Regulatory peptides·2014
Same journal

Insulin-like growth factor-1 inhibits colonic smooth muscle cell apoptosis in diabetic rats with colonic dysmotility.

Regulatory peptides·2014
Same journal

Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats.

Regulatory peptides·2014
See all related articles

Related Experiment Video

Updated: Oct 5, 2025

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.1K

CART peptides.

M J Kuhar1, L D Adams, R G Hunter

  • 1Yerkes Regional Primate Research Center of Emory University, 954 Gatewood Road NE, Atlanta, GA 30329, USA. mkuhar@rmy.emory.edu

Regulatory Peptides
|April 20, 2000
PubMed
Summary
This summary is machine-generated.

Cocaine and amphetamine-regulated transcript (CART) peptides are novel neurotransmitters. These peptides are involved in essential functions like feeding, stress, and reward pathways.

More Related Videos

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.5K
MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

11.4K

Related Experiment Videos

Last Updated: Oct 5, 2025

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids
10:23

Author Spotlight: Optimization of Ultrashort Peptide Matrices for Colorectal Cancer Organoids

Published on: May 3, 2024

1.1K
A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
10:42

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid

Published on: February 27, 2019

9.5K
MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent
06:54

MR Molecular Imaging of Prostate Cancer with a Small Molecular CLT1 Peptide Targeted Contrast Agent

Published on: September 3, 2013

11.4K

Area of Science:

  • Neuroscience
  • Molecular Biology
  • Endocrinology

Background:

  • Cocaine and amphetamine-regulated transcript (CART) peptides represent a newly identified class of peptide neurotransmitters/cotransmitters.
  • These peptides exhibit unique molecular characteristics, showing no significant homology with other known peptide families.
  • Emerging evidence suggests their involvement in a diverse range of physiological processes.

Purpose of the Study:

  • To elucidate the functional roles of CART peptides.
  • To understand the implications of CART peptides in neurobiology and behavior.

Main Methods:

  • Comparative sequence analysis to establish novelty.
  • Functional assays to investigate physiological roles (details not provided in abstract).

Main Results:

  • CART peptides are structurally distinct from other known peptides.
  • Hypothesized roles in reward, reinforcement, feeding, development, sensory processing, stress, and endocrine control.

Conclusions:

  • CART peptides are a unique class of signaling molecules.
  • Further research is warranted to fully characterize their mechanisms and functions in various biological systems.