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Published on: January 8, 2019
Lung function values in healthy children (10-15 years)
P P Sharma1, P Gupta, R Deshpande
1Department of Pediatrics and Physiology, University College of Medical Sciences, Delhi.
Insights
This study established pulmonary function norms for healthy Delhi children aged 10-15. Boys showed higher FEV1 and FVC, with lung function increasing with age in both sexes.
Area of Science:
- Pediatric Pulmonology
- Respiratory Physiology
Background:
- Establishing accurate pulmonary function norms is crucial for diagnosing respiratory conditions in children.
- Previous studies may not reflect current demographics or environmental factors in urban Indian populations.
Purpose of the Study:
- To establish age- and sex-specific reference norms for pulmonary function tests in healthy urban children aged 10-15 years in Delhi.
- To develop prediction equations for lung function parameters using anthropometric variables.
Main Methods:
- Pulmonary function tests were conducted on 222 boys and 188 girls (ages 10-15) from middle-income families in East Delhi using an electronic spirometer.
- Data were analyzed to determine lung function values (FEV1, FVC, PEFR, FRC, TLC) stratified by age and sex.
- Prediction equations were derived using height, age, and weight via a forward selection method.
Main Results:
- All pulmonary function parameters increased with advancing age.
- Boys exhibited significantly higher Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC) compared to girls.
- Peak Expiratory Flow Rate (PEFR), Functional Residual Capacity (FRC), and Total Lung Capacity (TLC) were similar between sexes until age 13, after which boys showed higher values.
- Height was the most significant predictor of lung function variance.
Conclusions:
- The study provides essential reference standards for pulmonary function in well-nourished urban Delhi children aged 10-15.
- These norms can aid in the clinical assessment and diagnosis of respiratory health in this specific pediatric population.
- Height is a key determinant of lung function in this age group.
Abstract:
The present study was designed to establish norms for pulmonary functions in urban healthy children of Delhi under the age group of 10-15 years. Pulmonary functions were assessed using an electronic lung function spirometer in 222 boys and 188 girls belonging to middle income group families of East Delhi. The pulmonary functions were separated by age and sex. All pulmonary functions showed an increase with advancing age. FEV1 and FVC were more in boys as compared to girls. Values of PEFR, FRC and TLC were similar in both sexes till the age of 13 years after which boys attained higher values. Prediction equations were obtained using height, age and weight as independent variables. Forward selection method was used to choose the best equation for each pulmonary function. Maximum variance in the lung functions was explained with the height. It is felt that norms established in the present study will act as reference standards for various lung functions in well nourished urban Delhi children under the age group of 10-15 years.
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