Related Experiment Video

Updated: Sep 14, 2026

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS
06:34

Identification of Rare Bacterial Pathogens by 16S rRNA Gene Sequencing and MALDI-TOF MS

Published on: July 11, 2016

Melioidosis--rare or overlooked?

M U Sanklecha1, K Raghavan, M N Mehta

  • 1Department of Pediatrics, L.T.M. Medical College, Sion, Mumbai.

Indian Journal of Pediatrics
|March 1, 1997
PubMed

Insights

Melioidosis is a rare bacterial infection often overlooked in medical literature. These two Indian cases highlight its potential significance and the need for increased awareness in clinical practice.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Clinical Case Reports

Background:

  • Melioidosis, caused by Burkholderia pseudomallei, is often perceived as an exotic and rare disease.
  • Its clinical presentation can be diverse, leading to diagnostic challenges.
  • Geographical distribution and endemicity are crucial factors in understanding disease prevalence.

Observation:

  • Presents two distinct cases of melioidosis originating from India.
  • Highlights the occurrence of this infection in a region where it might be underdiagnosed.
  • Emphasizes the importance of considering melioidosis in differential diagnoses.

Findings:

  • The cases serve as an educational tool, challenging the notion of melioidosis as a purely exotic disease.
  • Demonstrates the reality of melioidosis occurrence in specific geographical contexts.
  • Underscores the need for heightened clinical suspicion and diagnostic vigilance.

Implications:

  • Increased awareness of melioidosis in non-traditional endemic areas is crucial for timely diagnosis and treatment.
  • These case reports can inform public health strategies and clinical guidelines.
  • Further research into the epidemiology and clinical spectrum of melioidosis in India is warranted.

More Related Videos

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis07:27

Simplified Whole Body Plethysmography to Characterize Lung Function During Respiratory Melioidosis

Published on: February 24, 2023

Related Concept Videos

Pulmonary Tuberculosis III01:31

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Tuberculosis01:23

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...
Toxoplasmosis01:28

Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...