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Visualization of Recombinant DNA and Protein Complexes Using Atomic Force Microscopy
Published on: July 18, 2011
Direct measurement of DNA by means of AFM
1Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, The University of Tokushima, Japan.
Nucleic Acids Symposium Series
|April 26, 2000
Abstract:
We have demonstrated that the electrostatic stretch-and-positioning method is useful for the analysis of a long DNA molecule by means of atomic force microscopy (AFM). DNA molecules were stretched parallel to the field line, and immobilized onto the aluminum electrodes patterned on a glass plate. Through AFM observation, we confirmed the immobilization of individual DNA molecules, not aggregate.

