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Pseudomonas orbital cellulitis.

I S Weiss

    American Journal of Ophthalmology
    |March 1, 1979
    PubMed
    Summary
    This summary is machine-generated.

    A 3-month-old infant developed severe orbital cellulitis caused by Pseudomonas aeruginosa, leading to corneal perforation and endophthalmitis. This case highlights the aggressive nature of gram-negative infections in infants and the importance of prompt diagnosis and treatment.

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    Area of Science:

    • Ophthalmology
    • Pediatric Infectious Diseases
    • Microbiology

    Background:

    • Orbital cellulitis can rapidly progress to severe ocular complications.
    • Gram-negative bacterial infections, particularly Pseudomonas aeruginosa, pose a significant risk in neonates and young infants.
    • Early recognition and appropriate antimicrobial therapy are crucial for managing serious infections in this age group.

    Observation:

    • A 3-month-old infant with bronchitis presented with symptoms of orbital cellulitis.
    • The infant was treated with systemic gentamicin and ampicillin.
    • Despite treatment, a large corneal ulcer with globe perforation and endophthalmitis developed.

    Findings:

    • Pseudomonas aeruginosa was identified as the causative agent, cultured from blood, conjunctiva, and throat.

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  • The final diagnosis was Pseudomonas orbital cellulitis with secondary corneal perforation and endophthalmitis.
  • The respiratory tract was suspected as the primary source of infection.

    • Implications:

    • This case underscores the potential for aggressive Pseudomonas aeruginosa infections to cause devastating ocular outcomes in infants.
    • It emphasizes the need for vigilant monitoring and potentially broader-spectrum antibiotics in cases of suspected gram-negative sepsis with orbital involvement.
    • Prompt ophthalmologic consultation and intervention are critical for preserving vision in such severe cases.