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Synthesis and antimicrobial activity of (E)-acetoxystilbenes and alpha,alpha'-dibromoacetoxybibenzyls
E Wyrzykiewicz1, A Błaszczyk, B Kedzia
1Faculty of Chemistry, Adam Mickiewicz University, Poznań, Poland.
Abstract:
The synthesis of 13 new (E)-acetoxystilbenes and alpha,alpha'-dibromoacetoxybibenzyls and their antimicrobial activity are reported. The results of microbiological screening of 17 (E)-stilbenols and (E)-acetoxystilbenes, unknown in the literature, have also been discussed. In particular, coumpounds 1c, 1g, 2a, 3a, 3b, 4a, 6a, 6b showed good antibacterial activity against Staphylococcus aureus and 1c also against Bacillus subtilis.