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[Phenotypic expression of Lp(a) in Spanish children and adolescents]
J A Gómez Gerique1, D López Martínez, P Cancelas
1Departamento de Bioquímica Clínica, Fundación Jiménez Díaz, Madrid. jagomezg@meditex.es
Medicina Clinica
|April 27, 2000
Abstract
Background:
To know the distribution of phenotypes Lp(a) in an young population.
Methods:
Lipoprotein levels, lipoprotein(a), apolipoproteins and the Lp(a) phenotypes were determined in 105 children, selected according to their cholesterol concentrations.
Results:
The Lp(a) concentrations were significantly higher in group with low molecular weight respect to group with high molecular weight. The most frequent isoform was S3.
Conclusions:
The Lp(a) concentrations correlate inversely with the molecular weight of Apo(a) isoforms.