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Central auditory processing in patients with auditory hallucinations.

C M McKay1, D M Headlam, D L Copolov

  • 1Department of Otolaryngology and Human Communication Research Centre, University of Melbourne, East Melbourne, Australia. c.mckay@medoto.unimelb.edu.au

The American Journal of Psychiatry
|April 28, 2000
PubMed
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Auditory hallucinations in schizophrenia may stem from central auditory processing deficits, particularly in higher brainstem or cortical functions. Hallucinating patients showed greater deficits than non-hallucinating patients in specific auditory tests.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Auditory Processing

Background:

  • Schizophrenia is often accompanied by auditory hallucinations.
  • The underlying neural mechanisms of these hallucinations are not fully understood.
  • Central auditory processing is a potential area of investigation.

Purpose of the Study:

  • To investigate the association between auditory hallucinations and abnormalities in central auditory processing in schizophrenia patients.
  • To compare auditory processing in hallucinating patients, non-hallucinating patients, and healthy controls.

Main Methods:

  • Auditory assessments including auditory brainstem response and speech perception tests were administered to three groups: hallucinating patients, non-hallucinating patients, and normal subjects.
  • Statistical analyses (ANOVA, Kruskal-Wallis) were used to compare group performance.

Related Experiment Videos

  • Individual patient data with severely abnormal scores were analyzed for patterns of dysfunction.

    • Main Results:

    • No group differences were found in tests of low brainstem function.
    • Both patient groups exhibited deficits in tests sensitive to cortical or high brainstem function.
    • Hallucinating patients showed poorer performance on filtered speech perception and distinct response bias patterns on dichotic speech tests compared to non-hallucinating patients.

    Conclusions:

    • Auditory hallucinations in schizophrenia may be linked to auditory processing dysfunction in the right hemisphere or interhemispheric pathways.
    • The observed deficits in hallucinating patients might represent a more severe form of the same deficits present in non-hallucinating patients.