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Clinical experience in enteral nutrition support for premature infants with bronchopulmonary dysplasia

M A Puangco1, R J Schanler

  • 1Section of Neonatology, Baylor College of Medicine, Houston, TX, USA.

Journal of Perinatology : Official Journal of the California Perinatal Association
|April 29, 2000
PubMed

Insights

A 30 kcal/oz ready-to-feed formula offers comparable nutrition and feeding tolerance for premature infants with bronchopulmonary dysplasia (BPD). This formula also demonstrated improved protein status compared to supplemented preterm formulas.

Area of Science:

  • Neonatology
  • Pediatric Nutrition
  • Respiratory Medicine

Background:

  • Infants with bronchopulmonary dysplasia (BPD) often require fluid restriction.
  • Modular nutrient fortification of preterm formulas can enhance energy and protein but may affect nutrient integrity.
  • Optimizing nutrition for BPD infants is crucial for growth and development.

Purpose of the Study:

  • To compare the nutritional status and feeding tolerance of premature infants with BPD.
  • To evaluate a 30 kcal/oz ready-to-feed formula against a supplemented preterm formula in fluid-restricted BPD infants.

Main Methods:

  • A pilot study involving 27 premature infants diagnosed with BPD and undergoing fluid restriction.
  • Infants were randomized to receive either a 30 kcal/oz ready-to-feed formula or a concentrated preterm formula (30 kcal/oz) with nutrient additives.
  • Key outcomes measured included feeding tolerance, growth parameters, and biochemical markers of nutritional status.

Main Results:

  • No significant differences were observed in growth or feeding tolerance between the two formula groups.
  • Infants receiving the ready-to-feed formula showed improved serum albumin and blood urea nitrogen concentrations.
  • These findings suggest a potential benefit in protein nutritional status with the ready-to-feed option.

Conclusions:

  • A 30 kcal/oz ready-to-feed formula is a safe and effective alternative for premature infants with BPD.
  • This formula provides comparable nutrient composition to supplemented preterm formulas.
  • It may offer advantages in protein nutritional status for this vulnerable population.
Abstract

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