Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Proteomics in medical microbiology.

P Cash1

  • 1Department of Medical Microbiology, University of Aberdeen, Foresterhill, Scotland. p.cash@abdn.ac.uk

Electrophoresis
|April 29, 2000
PubMed
Summary

Proteomics, the study of proteins, offers valuable insights into microbial gene expression and has advanced medical microbiology. Key challenges remain in analyzing complex bacterial populations and integrating proteomic and genomic data.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microbiota and cancer: current understanding and mechanistic implications.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same author

Proteomic analysis of the sheep caruncular and intercaruncular endometrium reveals changes in functional proteins crucial for the establishment of pregnancy.

Reproduction (Cambridge, England)·2014
Same author

Proteomic analysis of ampicillin-resistant oral Fusobacterium nucleatum.

Oral microbiology and immunology·2008
Same author

A sensitive and reliable reverse transcriptase PCR-enzyme-linked immunosorbent assay for the detection of human pathogenic viruses in bivalve molluscs.

Journal of food protection·2007
Same author

A reliable RT-PCR-ELISA method for the detection of infectious pancreatic necrosis virus (IPNV) in farmed rainbow trout.

Journal of virological methods·2005
Same author

Sensing and adapting to acid stress.

Antonie van Leeuwenhoek·2002

Area of Science:

  • Microbiology
  • Molecular Biology
  • Biochemistry

Background:

  • Proteomics techniques, including 2D electrophoresis, analyze global protein synthesis to understand gene expression in microbes.
  • The availability of whole genome sequences has accelerated progress in microbial proteomics.

Purpose of the Study:

  • To review the current progress and applications of proteomics in medical microbiology.
  • To highlight existing technical challenges in applying proteomics to medical microbiology research.

Main Methods:

  • High-resolution two-dimensional electrophoresis for protein separation.
  • Protein characterization techniques for identification and analysis.

Main Results:

  • Proteomics aids in understanding microbial gene expression and has applications in epidemiology, taxonomy, and drug resistance analysis of pathogens.
  • Proteomics provides complementary insights to genomic investigations in medical microbiology.

Conclusions:

  • Proteomics has significantly contributed to medical microbiology, offering new perspectives on pathogens.
  • Future challenges include analyzing heterogeneous bacterial populations, integrating proteomic and genomic data, and characterizing pathogen proteomes in host environments.

Related Experiment Videos