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Related Experiment Videos

Interventions for promoting smoking cessation during pregnancy.

J Lumley1, S Oliver, E Waters

  • 1Centre for the Study of Mothers' and Children's Health, La Trobe University, 251 Faraday St, Carlton, Vic, Australia, 3053. j.lumley@latrobe.edu.au

The Cochrane Database of Systematic Reviews
|May 5, 2000
PubMed
Summary

Smoking cessation programs during pregnancy effectively reduce smoking rates, leading to decreased low birthweight and preterm birth. However, these programs did not significantly impact very low birthweight or perinatal mortality rates.

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Area of Science:

  • Obstetrics and Gynecology
  • Public Health
  • Neonatology

Background:

  • Maternal smoking is a significant risk factor for adverse pregnancy outcomes, including low birthweight, preterm birth, and perinatal death.
  • Identifying effective interventions to support smoking cessation in pregnant individuals is crucial for improving maternal and infant health.

Purpose of the Study:

  • To systematically review the evidence on the effectiveness of smoking cessation programs implemented during pregnancy.
  • To evaluate the impact of these programs on fetal, infant, maternal, and family health outcomes.

Main Methods:

  • Searched Cochrane Pregnancy and Childbirth Group and Cochrane Tobacco Addiction Group trials registers for randomized and quasi-randomized trials.
  • Assessed trial quality and extracted data independently by two reviewers.

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  • Included 44 trials, with 37 trials (16,916 women) providing data on smoking cessation and perinatal outcomes.

    • Main Results:

    • Smoking cessation programs significantly reduced smoking rates during pregnancy (OR 0.53, 95% CI 0.47 to 0.60).
    • Interventions led to a reduction in low birthweight (OR 0.80, 95% CI 0.67 to 0.95) and preterm birth (OR 0.83, 95% CI 0.69 to 0.99), with a mean birthweight increase of 28g.
    • No significant differences were observed for very low birthweight or perinatal mortality.

    Conclusions:

    • Smoking cessation programs implemented during pregnancy are effective in reducing smoking, low birthweight, and preterm birth.
    • While beneficial for several key outcomes, these programs did not demonstrate a significant effect on very low birthweight or perinatal mortality.