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Exercise for intermittent claudication.

G C Leng1, B Fowler, E Ernst

  • 1Primary Care and Population Sciences, Royal Free and University College Medical School, Royal Free Campus, Rowland Hill Street, London, UK, NW3 2PF. rfpc0015@rfhsm.ac.uk

The Cochrane Database of Systematic Reviews
|May 5, 2000
PubMed
Summary
This summary is machine-generated.

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See all related articles

Exercise significantly improves walking ability for individuals experiencing leg pain during walking, also known as intermittent claudication. This low-risk therapy offers substantial benefits compared to more invasive treatments.

Area of Science:

  • Vascular Medicine
  • Rehabilitation Science
  • Exercise Physiology

Background:

  • Intermittent claudication, characterized by leg pain during walking, significantly impacts quality of life.
  • Exercise presents a low-risk, cost-effective alternative to invasive therapies for managing intermittent claudication.

Purpose of the Study:

  • To systematically review the efficacy of exercise interventions for alleviating leg pain associated with intermittent claudication.

Main Methods:

  • A comprehensive search of multiple databases (Cochrane Peripheral Vascular Diseases Group, Embase) and trial registers was conducted.
  • Randomized controlled trials (RCTs) evaluating exercise regimens in patients with intermittent claudication were included.
  • Data extraction and quality assessment were performed independently by two reviewers, with efforts to obtain missing data from principal investigators.

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Main Results:

  • Ten high-quality RCTs involving approximately 250 patients with stable intermittent claudication were analyzed.
  • Exercise therapy demonstrated a significant improvement in maximal walking time (150% increase) compared to baseline.
  • Exercise outcomes were superior to angioplasty and antiplatelet therapy, and comparable to surgical treatment, though less effective than pentoxifylline in one trial.

Conclusions:

  • Exercise is a highly beneficial and effective treatment for patients suffering from leg pain due to intermittent claudication.
  • The findings support exercise as a primary therapeutic option, offering significant improvements in walking capacity and quality of life.