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Related Experiment Videos

Caffeine for asthma.

A I Bara1, E A Barley

  • 1Department of Public Health Sciences, St George's Hospital Medical School, Cranmer Terrace, Tooting, London, UK, SW17 ORE. airways@sghms.ac.uk

The Cochrane Database of Systematic Reviews
|May 5, 2000
PubMed
Summary
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Caffeine for asthma.

The Cochrane database of systematic reviews·2001

Caffeine consumption modestly improves lung function in asthma patients for up to four hours. This suggests avoiding caffeine before pulmonary function tests may be necessary.

Area of Science:

  • Pharmacology
  • Respiratory Medicine
  • Clinical Trials

Background:

  • Caffeine shares chemical similarities with theophylline, an asthma medication.
  • Previous studies suggest caffeine may alleviate asthma symptoms.
  • This review systematically examines existing evidence on caffeine's effects in asthma.

Purpose of the Study:

  • To assess caffeine's impact on lung function in adults with asthma.
  • To determine if caffeine consumption affects pulmonary function test (PFT) results.
  • To evaluate caffeine's potential as an asthma management aid.

Main Methods:

  • Systematic review of randomized controlled trials (RCTs).
  • Searched Cochrane Airways Group trials register and article reference lists.

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  • Included six high-quality, cross-over design trials involving 55 participants.

    • Main Results:

    • Caffeine demonstrated a modest improvement in lung function for up to 2 hours post-consumption.
    • Forced expiratory volume in one second (FEV1) showed a small, statistically significant improvement.
    • Mid-expiratory flow rates improved with caffeine, with effects sustained up to 4 hours.

    Conclusions:

    • Caffeine offers a modest, short-term improvement in airway function for individuals with asthma.
    • Patients may need to abstain from caffeine for at least 4 hours before undergoing lung function testing.
    • Further research could explore optimal caffeine dosages and long-term effects in asthma management.