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Updated: Aug 4, 2026
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Image-Guided Resection of Glioblastoma and Intracranial Implantation of Therapeutic Stem Cell-seeded Scaffolds
Published on: July 16, 2018
Biopsy versus resection for malignant glioma
1c/o Edinburgh Centre of Neuro-Oncology, Western General Hospital, Crewe Road, Edinburgh, Scotland, UK, EH4 2XU. s.metcalfe@sms.ed.ac.uk
The Cochrane Database of Systematic Reviews
|May 5, 2000
Summary
This review found no studies comparing surgical resection to biopsy for malignant glioma. Further research is needed to determine the best surgical approach for patients with these brain tumors.
Area of Science:
- Neurosurgery
- Oncology
- Clinical Trials
Background:
- Patients with supratentorial brain tumors face a choice between biopsy and resection.
- Surgical opinions are divided on the optimal management strategy due to risks and benefits.
- Malignant glioma requires careful consideration of surgical intervention.
Purpose of the Study:
- To evaluate the clinical effectiveness of radical surgical resection versus simple biopsy.
- To compare outcomes for malignant glioma patients undergoing different surgical procedures.
Main Methods:
- Comprehensive literature search of multiple electronic databases.
- Hand searching of journals and conference abstracts.
- Inclusion of randomized and clinical controlled trials comparing biopsy and resection.
Main Results:
- Extensive searches yielded 2100 citations, but no studies met inclusion criteria.
- Two potential articles were identified but subsequently excluded.
- No data could be synthesized due to the lack of qualifying studies.
Conclusions:
- No studies were identified to compare surgical resection with biopsy for malignant glioma.
- The lack of evidence highlights the need for a randomized controlled trial.
- Further research is crucial for patient risk, benefit, and health economics.
